Recharge

NAD+

Longevity Coenzyme

Best For

Anti-aging, energy optimization, cognitive support

50%

Decline in NAD+ levels by age 50

Sirtuin

NAD+-dependent longevity enzymes

PARP

DNA repair enzyme activation

How It Works

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme present in every living cell. It is essential for mitochondrial ATP production, serves as a substrate for sirtuin longevity enzymes (SIRT1-7), and is required by PARP enzymes for DNA repair. NAD+ levels decline approximately 50% by age 50, which is associated with mitochondrial dysfunction, impaired DNA repair, and accelerated aging.

Key Research Areas

Cellular Energy

Rate-limiting for mitochondrial ATP production

DNA Repair

Required substrate for PARP repair enzymes

Sirtuin Activation

Powers SIRT1-7 longevity enzyme family

Cognitive Support

Supports neuronal energy and neuroprotection

Research Highlights

  • Powers cellular energy, sirtuin activation, DNA repair
  • ~50% decline by age 50 — restoration supports all function

Formulation Notes

Common concentrations referenced in published clinical studies:

[KA-6500]500mg

Category

Recharge

NAD+ is the most critical coenzyme in metabolism — powering every cell's energy and essential for DNA repair. By 50, NAD...

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Educational Content. This compound profile is for informational purposes only. Not intended as medical advice, diagnosis, or treatment.